Volume 8, Issue 3 (2023)                   IJMPP 2023, 8(3): 900-903 | Back to browse issues page

Ethics code: IR.MODARES.AEC.1401.052

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Alami K, Jalali F, Azizi H. Early Life History of Drug Exposure Has Long Lasting Effect on Pain Sensitivity. IJMPP 2023; 8 (3) :900-903
URL: http://ijmpp.modares.ac.ir/article-32-69813-en.html
1- Department of Physiology, Fac- ulty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2- Department of Physiology, Fac- ulty of Medical Sciences, Tarbiat Modares University, Tehran, Iran , azizihf@yahoo.com
Abstract:   (446 Views)
Nowadays pain is the most commonly reported symptom in clinical practice. It is defined as “a complex emotional and sensorial experience that is associated with potential or actual damage” [1, 2]. Pain pathways represent a complex sensory system, with emotional, cognitive, and behavioral elements having evolved to detect and integrate a protective response to noxious stimuli [3, 4]. The protective nature of pain is true for acute pain, which is provoked by a specific disease or injury. However, chronic pain is not protective and is considered a disease state [5]. Pain sensitivity is one of the factors that determine the perceived severity, course, prognosis, and also treatment efficacy of clinical pain. It can be defined as increased or decreased pain responsiveness to noxious or non-noxious stimuli [6, 7]. Reduced sensitivity to pain is associated with the risk of delayed diagnosis or undermined treatment efficacy of conditions associated with acute pain. On the contrary, hypersensitivity is unpleasant and increases health care costs, risk of anxiety, and susceptibility to chronic pain conditions [8, 9]. Pain sensitivity widely varies among different individuals. There are several reports that factors, including genetic and environmental factors, affect an individual pain perception and sensitivity [8]. One of the environmental factors affecting pain perception that has not yet received much attention is the history of drug abuse [10].
Full-Text [PDF 284 kb]   (152 Downloads)    
Article Type: Brief Communication | Subject: Musculoskeletal Pain Prevention
Received: 2023/06/14 | Accepted: 2023/07/4 | Published: 2023/10/20

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.