The Coexistence of Pain and Depression Could be as a Factor for Diagnosis of Multiple Sclerosis

Document Type : Letter to Editor

Author
F. Moeini Badi
1Student Research Committee, School of Allied Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. 2 Nutrition and Metabolic Diseases Research Center and Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
10.22034/ijmpp.8.4.943
Abstract
Multiple sclerosis (MS) is a disease where the immune system attacks the central nervous system (brain and spinal cord) and causes damage over time. There are 28 million people who have MS, and the number of people with the disease has been increasing since 2013. In Iran, the rate of MS is highest in Tehran and lowest in Khuzestan and SistanBaluchestan provinces. The prevalence of pain in multiple sclerosis patients ranges between 29% and 86%. Moreover, the Prevalence of depression in MS is 24% to 50%. Pain in multiple sclerosis (MS) has been linked to different factors like a person's social and economic situation, chronic disease, and mental health conditions. Pain and depression are prevalent in newly diagnosed MS. In particular, pain has been related to higher disability, depression, and fatigue.

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1. Ghajarzadeh M, Foroushani AR, Ghezelbash P, Ghoreishi A, Maghbooli M, Yousefi M, et al. Prevalence of multiple sclerosis (MS) in Zanjan province of Iran. Int J Prev Med. 2020;11.
2. Walton C, King R, Rechtman L, Kaye W, Leray E, Marrie RA, et al. Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS. Multiple Sclerosis Journal. 2020;26(14):1816-21.
3. Mirmosayyeb O, Shaygannejad V, Bagherieh S, Hosseinabadi AM, Ghajarzadeh M. Prevalence of multiple sclerosis (MS) in Iran: a systematic review and meta-analysis. Neurol Sci. 2022;43:233-41.
4. Urits I, Adamian L, Fiocchi J, Hoyt D, Ernst C, Kaye AD, et al. Advances in the understanding and management of chronic pain in multiple sclerosis: a comprehensive review. Curr Pain Headache Rep. 2019;23:1-11.
5. Marrie RA, Reingold S, Cohen J, Stuve O, Trojano M, Sorensen PS, et al. The incidence and prevalence of psychiatric disorders in multiple sclerosis: a systematic review. Multiple Sclerosis Journal. 2015;21(3):305-17.
6. Marck CH, De Livera AM, Weiland TJ, Jelinek PL, Neate SL, Brown CR, et al. Pain in people with multiple sclerosis: associations with modifiable lifestyle factors, fatigue, depression, anxiety, and mental health quality of life. Front Neurol. 2017;8:461.
7. Valentine TR, Alschuler KN, Ehde DM, Kratz AL. Prevalence, co-occurrence, and trajectories of pain, fatigue, depression, and anxiety in the year following multiple sclerosis diagnosis. Multiple Sclerosis Journal. 2022;28(4):620-31.
8. Łabuz-Roszak B, Niewiadomska E, Kubicka-Bączyk K, Skrzypek M, Tyrpień-Golder K, Majewska A, et al. Prevalence of pain in patients with multiple sclerosis and its association with anxiety, depressive symptoms and quality of life. Psychiatr Pol. 2019;53(2):475-86.
9. Heitmann H, Haller B, Tiemann L, Mühlau M, Berthele A, Tölle TR, et al. Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study. Pain. 2020;161(4):787-96.
10. Solaro C, Gamberini G, Masuccio FG. Depression in multiple sclerosis: epidemiology, aetiology, diagnosis and treatment. CNS drugs. 2018;32(2):117-33.
International Journal of Musculoskeletal Pain Prevention
Volume 8, Issue 4
January 2023
Pages 943-944